Inverse problems arise in scientific applications such as biomedical imaging, computer graphics, computational biology, and geophysics, and computing accurate solutions to inverse problems can be both mathematically and computationally challenging.
Assume that
and
are given, then a linear inverse problem can be
written as
In this work, we are interested in finding a low rank optimal
regularized inverse matrix
that gives a small reconstruction error. That is,
should be small for some given error measure
, e.g.,
. The particular choice of
and
determine the regularization matrix
. Notice that once
is found we can efficiently compute
by simple
matrix-vector multiplication
. Our
approach is especially suitable for large scale problems
where (1) is solved repeatedly for various
.
In this talk, we focus on efficient approaches to numerical compute
optimal low-rank regularized inverse matrices. In real-life applications,
probability distributions
and
are typically not known explicitly.
However, in many applications, calibration or training data are readily
available, and this data can be used to compute a good regularization
matrix.
Let
for
, where
and
are
independently drawn from the corresponding probability distributions.
Then the goal is to solve the empirical Bayes risk minimization
problem,